Pulmonary Hemorrhage and Hemosiderosis in Infants

Pediatric Pulmonary
Dorr G. Dearborn, Ph.D., M.D.
Michael D. Infeld, M.D.
Pediatric Critical Care
Paul G. Smith, D.O.
Environmental Hygiene
Terrence M. Allan, M.P.H.
Cuyahoga County Board of Health
Stachybotrys (dark area) as found on drywall.
Over the past several years, there have been a
number of young infants (most under 6 months old), in the eastern
neighborhood of Cleveland, who have been coughing up blood due to
bleeding in their lungs. Some infants have died and more infants
continue to get ill. This bleeding, a disorder called Pulmonary
Hemorrhage appears to be caused by something in their home environments,
most likely toxins produced by an unusual fungus called Stachybotrys
chartarum or similar fungi.
What is Pulmonary Hemosiderosis?
Bleeding in the lungs.
What Are The Symptoms?
Severe bleeding can cause coughing up blood or
nose bleeds. This is particularly concerning in infants under 6 months
old. Chronic, low grade bleeding can cause chronic cough and congestion
with anemia. Aside from infants bleeding, there are still many symptoms
of contamination from
Stachybotrys
chartarum
or other similar fungi.
[Please
note: you can read Mold Inspector insights by clicking:
Mold/Fungi.]
What Causes The Bleeding?
Most likely, toxins made by an unusual fungus
or mold Stachybotrys. When infants breathe in the toxins, the
blood vessels in their lungs may become fragile. The weak vessels may be
bothered by cigarette smoke or stresses from other illnesses and start
to bleed. You cannot see the toxins in the air rather they are carried
in the microscopic fungal spores.
[ Please note: to find out more info on symptoms of
contamination from
Stachybotrys
chartarum or similar fungi and its effects, please visit:
Mold/Fungi]
How Do I Know If The Fungus Or Mold Is
In My House?
This fungus or mold grows only on wood or paper
that have gotten very wet for more than a few days or so. (It does NOT
grow on plastic, vinyl, concrete products, or ceramic tiles). If the
wood/paper gets wet and is not cleaned up and dried, the fungus may grow
and spread. The fungus is black and slimy when wet. It is NOT
found in the green mold on bread or the black mold on the shower tiles
(but the shower tiles should be kept clean too). If you have had
plumbing leaks, roof leaks, flooding in the basement (even if you don't
use the basement), or sewer backup in the past year, look for mold or a
musty odor.
[Please note: For more info on how this dangerous mold grows
and spread in your home, please visit:
Mold/Fungi
,
Toxic Mold
Inspector
, or
Certified Mold Contractor.
Common Areas for This Mold Growth:
Water soaked wood, ceiling tiles, wall
paneling, unpainted plaster board surfaces, cotton items, cardboard
boxes, and stacks of newspapers. If these areas have been very wet,
usually for longer than one week, check for mold. After the area dries,
the fungus will not continue to grow, but the black dust caused by the
fungus can be sucked up by the furnace blower and spread throughout the
house. Be sure and check your basement for the black mold. If you do not
have access to the basement, ask your landlord for assistance. Note:
not all black mold is Stachybotrys, but moldy homes are not
healthy homes.
Heating Systems:
If you have mold in your basement, check to see
if there is any way that your forced air furnace can send the mold dust
up to the living spaces. Is there ductwork connecting the cold air
returns to your furnace or does your furnace pull air from the basement?
The latter is the case if you can see the furnace filter face on
(rather than just the edge).
Please note: For more information on how to Remove
or Remediate Mold Growth, please click on the following websites:
Mold Removal or
Mold Testing.
THE
CLEVELAND OUTBREAK
Over the past seven years in the Cleveland,
Ohio area there have been 45 cases of pulmonary hemorrhage (PH) in young
infants. Sixteen of the infants have died. Thirty-two of the infants
have been African American. Most of these cases have occurred within ten
contiguous zip codes area in the eastern portion of the metropolitan
area. In November/December, 1994, the Centers for Disease Control and
Prevention (CDC) lead a case-control investigation on the first ten
cases. This study found an epidemiological association of PH in these
infants with water-damaged homes containing the toxic fungi,
predominantly Stachybotrys. Several lines of evidence
suggest that the most likely causal agents are fungal toxins from a
fungus called Stachybotrys atra. This somewhat unusual fungus
was found in high quantity in the home environments of the affected
infants but also to a lesser degree in some of the comparison homes. Stachybotrys
requires water soaked cellulose to grow, and was found in homes where
there had been water damage from flooding, plumbing leaks or roof leaks
involving wood or paper products (e.g. insulation, gypsum board, ceiling
tile). The spores of this fungus contain very potent mycotoxins which
appear to be particularly toxic to the rapidly growing lungs of young
infants. The linkage of Stachybotrys to PH in infants is on the
basis of epidemiological data and has not been conclusively
demonstrated. Other factors such as environmental tobacco smoke appear
to be important triggers in precipitating overt pulmonary hemorrhage.
More cases continue to occur, a few infants
having had only very subtle initial symptoms such as nose bleeds and
chest congestion. Concern that there may be a larger number of
undetected young infants with this disorder, led to the examination of
all infant coroner cases over a three year period, 1993-1995. This
revealed seven "SIDS" (sudden infant death syndrome) cases
with evidence of preexisting major pulmonary bleeding. All but one of
these infants had lived in the ten zip code cluster area.
This disorder is likely to extend beyond
Cleveland since an informal national survey of all pediatric pulmonary
centers and continued reporting has identified over 100 similar cases of
pulmonary hemorrhage in infants across the country over the last seven
years.
IS MY
MOLD STACHYBOTRYS?
While Stachybotrys chartarum (atra)
occurs widely in North America, it is probably rather uncommon to find
it in homes. It requires water soaked cellulose (wood, paper, and cotton
products) to grow. While wet it looks black and slimy perhaps with the
edges white, and when dry it looks less shiny. It is not the
only or the most common black mold to be found in these conditions. If
your clean-up is not simple, i.e. your water damage and mold growth is
extensive and/or involves structural materials, contact your city or
county health department for assistance in assessing the problem. They
can put you in contact with environmental laboratories capable of
identifying Stachybotrys and with abatement contractors
familiar with the precautions and other specifics important for
extensive inspection. If you have a large area of mold growth (greater
than two square feet or so), seek professional assistance in mold
remediation. You can get quite ill yourself if you inhale a large quantity
of the fungal dust or get it on your skin.
[Please note: for information on mold
testing and mold removal, please visit these very helpful websites.]
Mold Removal and Remediation.
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